Formulation & Development
At Pyramid Pharma Services, you’ll have one team, together in one site, working toward one goal: the successful design and development of your project. To get there, we harness our decades of experience in liquid and lyophilization cycle development along with our long history of expertise in analytical methods that inform our work.
Our process
Intelligent Drug Design—Your Long-Term Goals in Mind
Whether your product is a small molecule or a biotech pharmaceutical (protein, peptide or oligonucleotide), we can support the design and execution of pre-formulation and formulation development studies that will help define your final drug product formulation.
01
Formulation Development
We integrate formulation development with primary packaging selection and process design phases to yield a parenteral product that meets or exceeds your performance expectations for a clinical drug—and, ultimately, for a marketable product.
02
Lyophilization
Should you choose to lyophilize your drug product, PYRAMID has the experience and tools necessary to help design a stable dosage form, along with an effective and efficient lyophilization cycle.
03
Stabilization Strategies
Our scientists have an armamentarium of successful formulation strategies to stabilize sensitive protein and peptide pharmaceuticals. Our differential scanning calorimeter and lab scale lyophilizers enable us to establish the optimum lyophilization cycle parameters for your drug product.
Our services
Here for Every Stage of Your Development Lifecycle
Flexibility and collaboration govern our partnership. We’ll tailor our services to meet your needs as you develop your product formulation and complete your stability studies.
Drug Product Development
Formulation & process development for liquid & lyophilized products
Lyophilization
Development and GMP manufacturing for lyophilized drug products
Clinical Manufacturing
GMP manufacturing & distribution for clinical trials
Commercial Manufacturing
GMP Drug Product Manufacturing for International Markets
Biologics & Novel Modalities
Drug product development & manufacturing for biologics and other novel modalities
Analytical Services & QC Testing
Method development, validation and testing
Stability Studies
Short-term & long-term stability studies at all ICH conditions
Quality Assurance & Regulatory Support
Our dedicated Quality Assurance team ensures that all work is conducted in strict compliance
Labeling, Storage & Distribution
ICH-compliant GMP storage. Global distribution
Our capabilities
Our Development Know-How. Your Peace of Mind.
At Pyramid Pharma Services, we offer more than 37 years’ experience across all parenteral formulation and manufacturing—and we know that every project is unique. That’s why we take a collaborative approach, listening to your needs for your project, and delivering on those needs. Uniquely, we’re able to work across development and clinical & commercial manufacturing, so you will have one team dedicated to optimizing your product at every stage.
We offer in-depth expertise to assist your development efforts in:
- Liquid formulations
- Lyophilized formulations
- Suspension & dispersed-system dosage forms
- Manufacturing process design & optimization of existing processes
- Manufacturing scale-up & technology transfer
Our facilities
Where Scientific Meets Analytical
Our renowned analytical testing laboratory is an indispensable part of our development process. Our experienced analytical scientists can assist in developing stability-indicating analytical methods for your development studies, along with finished drug product release and stability studies. Additionally, we can transfer your existing methods to our lab. Our facility is equipped with stability incubators covering the full array of ICH temperature and humidity conditions to support these processes, with back-up power supply and continuous monitoring by a SCADA system.
How Can We Help?
Let us apply our 37+ years of experience to help you solve your development and supply challenges. Learn more about what it means to differentiate your development process with Pyramid Pharma Services.